Aside

Contact Info


Skills

Extended skills: genetic manipulation (in mouse), immunohistochemistry, confocal microscopy, electrophysiology, biochemistry, immunoprecipitation, SDS-PAGE, western blot, virus design, intracerebroventricular virus injection, primer design, PCR, 2-photon microscopy, glutamate uncaging, organotypic slice culture, biolistic transfection, genetically encoded fluorescent biosensors, experimental design, data analysis, figure design, Adobe Photoshop, Adobe Illustrator, R, Python, Bash, Git


References

Kevin M. Wright, PhD
Vollum Institute, OHSU
wrighke@ohsu.edu

Eric Schnell, MD, PhD
Anesthesiology and Perioperative Medicine, School of Medicine, OHSU
schneler@ohsu.edu

Karen Zito, PhD
Center for Neuroscience, UC Davis
kzito@ucdavis.edu



Disclaimer

This resume was made with the R package pagedown.

Last updated on 2023-09-20.

Main

Jennifer Jahncke

Portland, OR

Education

Oregon Health & Science University

PhD in Neuroscience

Portland, OR

Present - 2018

  • Advisor: Kevin M. Wright, PhD, Vollum Institute, OHSU

University of California, Davis

BS in Psychology, Minor in Neuroscience

Davis, CA

2014 - 2010

  • Genetics study abroad program in Cambridge, UK and Stockholm, Sweden (Summer 2012)

Selected Courses

  • Neurohackademy, UW, 2023, Seattle, WA
  • Programming for Biology, CSHL, 2022, Cold Spring Harbor, NY
  • Biostatistics, OHSU, 2020, Portland, OR
  • Data Visualization, OHSU, 2020, Portland, OR
  • Practice and Ethics of Science, OHSU, 2018, Portland, OR
  • Light and Fluorescence Microscopy, UC Davis, 2017, Davis, CA

N/A

Research Experience

Graduate Student Researcher

Neuroscience Graduate Program, OHSU

Portland, OR

Present - 2018

  • Functional characterization of the scaffolding protein Dystroglycan at inhibitory synapses across the brain in mouse models of dystroglycanopathy.
  • Identified novel interacting partners of Dystroglycan in the central nervous system.
  • Use of R, Python, and Igor to automate data analysis.

Staff Research Associate

Zito & Fioravante Labs, UC Davis

Davis, CA

2018 - 2014

  • Characterization of genetically encoded fluorescent glutamate sensors using 2-photon glutamate uncaging on dendritic spines in CA1 of the hippocampus.
  • Elucidation of a novel protein signaling cascade in non-ionotropic NMDA receptor mediated LTD.

Undergraduate Research Assistant

Trimmer & Trainor Labs, UC Davis

Davis, CA

2014 - 2011

  • Independent project: Profiling expression and localization of Kv2.1 & Kv2.2 voltage gated potassium channels in the developing rat hippocampus.
  • Assisted in a study investigating the role of D1 dopamine receptors in social withdrawal behavior associated with anxiety and depression.
  • Assisted in a project investigating kappa opioid receptors as a mechanism for behavioral differences between the sexes in response to stress.

HONORS

2023-2024 OHSU School of Medicine N.L. Tartar Trust Research Fellowship

2020-2023 Ruth L. Kirschstein National Research Service Award

2020 NSF GRFP Honorable Mention

ARCS Foundation Scholar

Phi Beta Kappa

Teaching Experience

OHSU NGP Bootcamp: Model Organisms

Hands on dissection of mouse and sheep brains.

Portland, OR

2023

Rigor and Reproducibility in Light Microscopy

Lecture on best practices in light microscopy, aimed at incoming neuroscience graduate students.

Portland, OR

2023

OHSU MD Foundations of Medicine: Nervous System and Function

Instruction of first year medical students learning about brain structure and function. Taught human cerebellum and brain stem anatomy in a hands on lab working with donated specimen.

Portland, OR

2023

OHSU NGP Bootcamp: Patch Clamp Electrophysiology

Hands on patch clamp instruction.

Portland, OR

2021

Graduate Level TA Positions

Biostatistics (CONJ 620) Winter 2020, OHSU
Cellular Neurophysiology (NEUS 624) Fall 2019, OHSU

Portland, OR

2020, 2019

MBL Neurobiology, Imaging Section

Teaching assistant at the Marine Biological Laboratory Neurobiology Course for the imaging section.

Woods Hole, MA

2018

Publications

An adhesion signaling axis involving Dystroglycan, β1-Integrin, and Cas adaptor proteins regulates the establishment of the cortical glial scaffold.

Wong W, Estep JA, Treptow AM, Rajabli N, Jahncke JN, Ubina T, Wright KM, Riccomagno MM. PLoS Biol. 2023 Aug 4;21(8):e3002212. doi: 10.1371/journal.pbio.3002212

N/A

2023

Inhibitory CCK+ basket synapse defects in mouse models of dystroglycanopathy.

Jahncke JN, Miller DS, Krush M, Schnell E, Wright KW. eLife. 2023 May 16; 12:RP87965. doi: 10.7554/eLife.87965.1

N/A

2023

The many roles of dystroglycan in nervous system development and function.

Jahncke JN, Wright KW. Developmental Dynamics. 2023; 252( 1): 61- 80. doi: 10.1002/dvdy.516

N/A

2023

Shared and Distinct Functional Effects of Patient-Specific Tbr1 Mutations on Cortical Development.

Co M, Barnard RA, Jahncke JN, Grindstaff S, Fedorov LM, Adey AC, Wright KM, O’Roak BJ. Journal of Neuroscience 14 September 2022, 42 (37) 7166-7181; doi: 10.1523/JNEUROSCI.0409-22.2022

N/A

2022

Molecular Mechanisms of Non-ionotropic NMDA Receptor Signaling in Dendritic Spine Shrinkage.

Stein IS, Park DK, Flores JC, Jahncke JN, Zito K. Journal of Neuroscience 22 April 2020, JN-RM-0046-20; doi: 10.1523/JNEUROSCI.0046-20.2020

N/A

2020

A Dual Role for the RhoGEF Ephexin5 in Regulation of Dendritic Spine Outgrowth.

Hamilton AM, Lambert JT, Parajuli LK, Vivas O, Park DK, Stein IS, Jahncke JN, Greenberg ME, Margolis SS, Zito K. Molecular and Cellular Neuroscience 80 (2017): 66-7 doi: 10.1016/j.mcn.2017.02.001

N/A

2017

Talks

Inhibitory Basket Synapse Formation in Mouse Models of Dystroglycanopathy

Vollum Works In Progress

Portland, OR

2023

A functional role for Dystroglycan at inhibitory cerebellar synapses

Vollum Works In Progress

Virtual

2021

Dystroglycan: a scaffold for inhibitory synapses in cerebellar cortex

Vollum Works In Progress

Virtual

2020

Abstracts

Dystrogycan is necessary for the formation of functional inhibitory CCK+/CB1R+ basket synapses in hippocampus.

Jahncke JN, Miller DS, Schnell E, Wright KM. CSHL Molecular Mechanisms of Neuronal Connectivity

Cold Spring Harbor, NY

2022

Purkinje cell Dystroglycan may promote the function of inhibitory basket synapses in cerebellar cortex.

Jahncke JN, Schnell E, Wright KM. CSHL Molecular Mechanisms of Neuronal Connectivity

Cold Spring Harbor, NY

2020

Non ionotropic NMDA receptor signaling mechanisms driving dendritic spine plasticity.

Stein IS, Park DK, Jahncke JN, Zito K. Society for Neuroscience

Chicago, IL

2019

Genetically-encoded glutamate sensors for monitoring large populations of individual synapses in vivo.

Mizuno GO, Dong C, Jahncke JN, Natan R, Papadopoulos S, Jaffe D, Lambert JT, Ji N, Zito K, Tian . Fourth Annual Brain Initiative Investigators Meeting

Bethesda, MD

2018

Volunteer & Mentorship Experience

Alliance for Visible Diversity (AVDS)

Communications Committee Member

Portland, OR

Present - 2020

OHSU Graduate School Organization (GSO)
Peer Mentoring Program

Peer Mentor

Portland, OR

2022 - 2019

Women In Science PDX (WIS)

STEMpowerment Committee Member

Portland, OR

2020 - 2019

NGP Alumni Invite Committee

Committee Member

Portland, OR

2019 - 2018

Brain Awareness Week - Davis Chapter

Event Organizer, Volunteer

Davis, CA

2018 - 2015

UC Davis Neurobiology, Physiology, & Behavior Club

Guest Speaker

Davis, CA

2015

Undergraduate Researcher Mentor

Mentored two undergraduates in the lab setting, overseeing their independent research projects and providing support through poster presentations, fellowship applications, and career development.

Davis, CA

2018 - 2014